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Onychomycosis. Going for cure

A K Gupta1, N H Shear

  • 1Department of Medicine, Sunnybrook Health Science Centre.

Canadian Family Physician Medecin De Famille Canadien
|February 1, 1997
PubMed
Summary
This summary is machine-generated.

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Newer antifungal drugs like terbinafine offer a more cost-effective treatment for onychomycosis compared to older medications. Terbinafine is the preferred choice in Canada for fungal nail infections.

Area of Science:

  • Dermatology
  • Mycology
  • Pharmacology

Background:

  • Onychomycosis is a common fungal nail infection.
  • Treatment options have evolved, necessitating a review of available antifungal agents.

Purpose of the Study:

  • To review traditional and newer antifungal agents for onychomycosis treatment.
  • To evaluate the cost-effectiveness of different antifungal therapies.

Main Methods:

  • Literature search of MEDLINE from 1966 to 1995.
  • Exclusion of case reports from the analysis.

Main Results:

  • Newer antifungal agents, including terbinafine, itraconazole, and fluconazole, are more cost-effective than griseofulvin and ketoconazole.
  • Terbinafine is the only newer agent approved in Canada for onychomycosis during the study period.

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Conclusions:

  • Newer antifungal drugs represent a significant advancement in treating onychomycosis.
  • Terbinafine is the recommended and most cost-effective agent for dermatophyte-induced onychomycosis in Canada.