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Potential antitumor agents. 25 [1]. Synthesis and cytotoxic activity of
A Andreani1, A Locatelli, M Rambaldi
1Dipartimento di Scienze Farmaceutiche, Università di Bologna, Italy.
Anticancer Research
|November 1, 1996
Abstract:
The Knoevenagel reaction between 2-indolinones and 2-chloroindolaldehydes gave 3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones which were tested as potential antitumor agents on cultures of HeLa cells. 2-Chloro derivatives with at least one unsubstituted NH group, are promising candidates for further investigation.