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International Continence Society "Benign Prostatic Hyperplasia" Study: background, aims, and methodology
P Abrams1, J L Donovan, J J de la Rosette
1Bristol Urological Institute, Southmead Hospital, UK.
Neurourology and Urodynamics
|January 1, 1997
Summary
The International Continence Society Benign Prostatic Hyperplasia Study (ICS-BPH) evaluated urodynamics for diagnosing benign prostatic obstruction (BPO). It found lower urinary tract symptoms (LUTS) have poor specificity for BPO, impacting treatment decisions.
Area of Science:
- Urology
- Andrology
- Diagnostic Medicine
Background:
- Underutilization of urodynamics in diagnosing benign prostatic obstruction (BPO).
- Over-reliance on symptoms alone for selecting invasive therapies.
- Lower urinary tract symptoms (LUTS) demonstrate poor diagnostic specificity for BPO.
Purpose of the Study:
- To assess the diagnostic potential of LUTS for BPO.
- To define the role of urine flow studies in BPO diagnosis.
- To identify patients requiring pressure flow studies before invasive treatment.
Main Methods:
- International multicenter study (ICS-BPH Study) involving 1271 patients.
- Utilized patient-completed questionnaires on symptoms, quality of life, and sexual function.
- Standardized urodynamic investigations and multiple urine flow studies were performed.
Main Results:
- 60% of patients were found to be obstructed via pressure flow studies.
- 83% of patients completed at least two urine flow studies.
- Identified varying degrees of obstruction: 18% unobstructed, 22% mildly obstructed.
Conclusions:
- The study aims to clarify the diagnostic value of LUTS and urine flow studies for BPO.
- It seeks to guide the selection of patients for invasive treatments based on urodynamic findings.
- Challenges exist in creating a diagnostic symptom score due to coexisting conditions.