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[Persistent foramen ovale and cerebral embolism]

T Mendel1

  • 1II Kliniki Neurologicznej Instytutu Psychiatrii i Neurologii w Warszawie.

Neurologia I Neurochirurgia Polska
|July 1, 1996
PubMed
Summary

Paradoxical embolism via persistent foramen ovale can cause cardiogenic cerebral embolism. Echocardiography and transcranial Doppler ultrasound (TCD) help assess stroke links and guide treatment.

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Area of Science:

  • Neurology
  • Cardiology
  • Vascular Medicine

Background:

  • Paradoxical embolism is a recognized cause of cardiogenic cerebral embolism.
  • Persistent foramen ovale (PFO) is a potential pathway for paradoxical embolism.
  • Ischemic stroke necessitates understanding embolic sources for effective management.

Purpose of the Study:

  • To elucidate the role of persistent foramen ovale in paradoxical embolism leading to ischemic stroke.
  • To highlight the diagnostic utility of specific imaging modalities in evaluating this condition.
  • To inform treatment strategies for patients experiencing ischemic stroke potentially related to PFO.

Main Methods:

  • Utilizing transesophageal echocardiography (TEE) to visualize cardiac structures and detect intracardiac shunts.
  • Employing transthoracic echocardiography (TTE) as a non-invasive method for cardiac assessment.
  • Implementing transcranial Doppler ultrasound (TCD) to evaluate cerebral blood flow and detect microembolic signals.

Main Results:

  • Echocardiographic methods confirmed the presence of PFO in relevant patient cohorts.
  • Diagnostic imaging established a link between PFO and the occurrence of ischemic stroke.
  • TCD provided additional data supporting embolic events originating from the PFO.

Conclusions:

  • Persistent foramen ovale represents a significant mechanism for cardiogenic cerebral embolism.
  • Echocardiography (TEE and TTE) and TCD are crucial diagnostic tools for assessing the PFO-stroke connection.
  • These diagnostic capabilities are essential for guiding appropriate and targeted treatment interventions.

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