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Updated: Jul 30, 2026

Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
Published on: April 15, 2021
[Views on the etiology and pathogenesis of intracranial saccular aneurysms]
P Ladziński1, R Koper, M Maliszewski
1Oddziału Neurochirurgii Szpitala Górniczego w Sosnowcu.
Abstract:
The anatomical structure of intracranial arteries may favour the development of aneurysms because of poorly developed external elastic lamina and adventitia, gaps in the muscular layer and great number of collagenous fibres. However, the haemodynamic factor has the principal significance in initiation, growth and rupture of the aneurysms. The importance of this factor is especially great in cases of coexistence with developmental abnormalities of the arteries, arterial occlusion, hypertension, atherosclerosis or hereditary connective tissue disorders.
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