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FlyBase: a Drosophila database. The FlyBase consortium

W M Gelbart1, M Crosby, B Matthews

  • 1FlyBase, Biological Laboratories, 16 Divinity Avenue, Cambridge, MA 02138, USA.

Nucleic Acids Research
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

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FlyBase is a comprehensive database for Drosophila genetic and molecular data. It provides access to genes, alleles, phenotypes, and bibliographic references, integrating with genome project data.

Area of Science:

  • Genetics
  • Molecular Biology
  • Bioinformatics

Background:

  • Drosophila melanogaster serves as a crucial model organism in biological research.
  • Comprehensive genetic and molecular data are essential for advancing Drosophila studies.

Purpose of the Study:

  • To describe the FlyBase database, a resource for Drosophila genetic and molecular information.
  • To highlight the integration of FlyBase with the Berkeley Drosophila Genome Project (BDGP).

Main Methods:

  • Data curation and integration into a relational database (Sybase).
  • Dissemination of information through HTML documents and flat files.
  • Collaboration with the Berkeley Drosophila Genome Project for data enrichment.

Main Results:

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  • FlyBase encompasses a wide range of data including genes, alleles, phenotypes, aberrations, and transposons.
  • Pointers to sequence data, clones, stock lists, and bibliographic references are included.
  • Integration with BDGP data enriches the resource through the Encyclopedia of Drosophila.

Conclusions:

  • FlyBase is a vital, continuously updated resource for the Drosophila research community.
  • The database facilitates research by providing integrated genetic and molecular information.
  • Collaboration enhances the scope and utility of FlyBase for biological discovery.