[Endogenous intoxication syndrome in critical states in infants. New diagnostic and prognostic possibilities]

New methods for the diagnosis of the endogenous intoxication syndrome (EIS) in critical states have been developed and tried in 585 infants. A complex of biochemical, hemorheological, biophysical, and optic polarization parameters characterizing the intensity of catabolic reactions and united under the term "endotoxicogram" is offered. Objective assessment of EIS is expressed by an integral index of intoxication which permits a universal assessment of the severity of patient's status, disease course, and efficacy of therapy and helps predict the disease outcome.