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Related Experiment Videos

Severe allergy to sorbolene cream

A R MacKenzie-Wood1, S Freeman

  • 1Skin and Cancer Foundation Australia, Darlinghurst, New South Wales, Australia.

The Australasian Journal of Dermatology
|February 1, 1997
PubMed
Summary

A patient developed allergic contact dermatitis to chlorocresol, a preservative in sorbolene cream, after years of occupational exposure. Delayed diagnosis highlights the importance of thorough patch testing for persistent dermatitis.

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Area of Science:

  • Dermatology
  • Allergology
  • Occupational Health

Background:

  • Occupational hand and foot dermatitis can significantly impact a patient's quality of life and career.
  • Barrier creams are often used in occupational settings to prevent skin irritation.

Observation:

  • A 40-year-old motor mechanic developed persistent hand and foot dermatitis while using sorbolene cream.
  • The patient was unable to continue his trade due to the severity of his dermatitis.

Findings:

  • A diagnosis of allergic contact dermatitis to chlorocresol was made 16 years after symptom onset.
  • Chlorocresol, a common preservative in sorbolene and corticosteroid creams, was identified as the allergen.
  • Initial patch testing in 1983 was negative, likely due to the omission of chlorocresol and sorbolene cream.

Implications:

  • This case underscores the importance of considering delayed-type hypersensitivity reactions in chronic dermatitis.
  • Thorough patch testing, including specific allergens and product vehicles, is crucial for accurate diagnosis.
  • Occupational dermatitis management requires identification and avoidance of causative agents.

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