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Intraparenchymal metastatic tumor with periventricular dissemination--case report
R Y Liu1, K Matsumoto, Y Yoshimoto
1Department of Neurological Surgery, Okayama University Medical School.
Abstract:
A 50-year-old male presented with a rare intraparenchymal metastatic tumor spreading through the periventricular tissue. Magnetic resonance (MR) imaging demonstrated the tumor as a heterogeneous low-intensity area on T1-weighted images with enhancement by gadolinium-diethylenetriaminepenta-acetic acid, and as a heterogeneous high- or isointensity area on T2-weighted images. Histological examination of a biopsy sample showed adenocarcinoma. This MR imaging appearance is typical of malignant glioma. The differential diagnosis of tumor in the cerebral parenchyma with ventricular dissemination should include both primary and secondary intracranial malignant tumors. MR imaging is useful in the diagnosis of such tumors, but the final diagnosis should be based on either tissue biopsy or cytological examination of the cerebrospinal fluid.
Insights
A rare intraparenchymal metastatic tumor spreading through periventricular tissue was identified in a 50-year-old male. Magnetic resonance (MR) imaging revealed characteristic features, with biopsy confirming adenocarcinoma, highlighting the importance of imaging and biopsy for diagnosis.
Area of Science:
- Neuro-oncology
- Radiology
- Pathology
Background:
- Intraparenchymal metastatic tumors spreading via periventricular tissue are rare.
- Accurate diagnosis is crucial for appropriate patient management.
- Magnetic resonance (MR) imaging plays a key role in characterizing intracranial lesions.
Observation:
- A 50-year-old male presented with a rare intraparenchymal tumor.
- MR imaging showed a heterogeneous lesion with specific signal intensities on T1 and T2 weighted images, and contrast enhancement.
- Histological examination of a biopsy confirmed adenocarcinoma.
Findings:
- The MR imaging appearance mimicked malignant glioma.
- Ventricular dissemination of tumors requires consideration of both primary and secondary intracranial malignancies.
- Adenocarcinoma was identified as the histological subtype.
Implications:
- MR imaging is valuable for diagnosing such rare tumors.
- Definitive diagnosis relies on tissue biopsy or cerebrospinal fluid cytology.
- Distinguishing between primary and secondary tumors is essential for treatment planning.