[Change of blood pressure in head-up tilting test in patients with Binswanger-type infarction]

Change of blood pressure was analysed after loading of 90 degrees head-up tilting for 10 minutes in patients with Binswanger-type infarction to clarify the hemodynamic disorder of this disease. In 79 controls (mean age; 70. 1 years), systolic and diastolic blood pressures on standing were higher than those of the supine position, respectively. There was no difference in orthostatic change of blood pressure between the controls and patients with lacunar infarction (40 cases, mean age; 66.1 years). On the other hand, in patients with Binswanger-type infarction (29 cases, mean age; 67.8 years), blood pressure tended to show a marked decrease after standing, especially in the male. Systolic blood pressure was generally lower than that of the supine position while standing. It is suggested that the fall of blood pressure on standing would play an etiological or deteriorative role in this disease.