Related Experiment Videos
Repeated lipoinjections for stress urinary incontinence
P C Palma1, C L Riccetto, V Herrmann
1Dept. of Urology, Faculdade de Ciências Médicas da Universidade Estadual de Campinas, UNICAMP, San Paulo, Brazil.
Journal of Endourology
|February 1, 1997
Summary
Repeated periurethral fat injections improved stress incontinence outcomes in women with intrinsic sphincteric deficiency. Sequential injections showed higher cure rates than single injections after one year.
Area of Science:
- Urology
- Minimally Invasive Surgery
Background:
- Stress urinary incontinence (SUI) affects many women.
- Intrinsic sphincteric deficiency (ISD) is a common cause of SUI.
- Autologous fat injection is a potential SUI treatment.
Purpose of the Study:
- To evaluate the efficacy of periurethral autologous fat injection for SUI in women with ISD.
- To compare outcomes between single and sequential injection protocols.
Main Methods:
- 30 women with SUI and ISD underwent periurethral fat injection.
- Fat was harvested via liposuction.
- Patients received either a single injection or sequential injections at 3-month intervals.
- Outcomes assessed via subjective questionnaires at 3 and 12 months.
Main Results:
- Sequential injection group had a 64% cure rate vs. 31% in the single injection group after 1 year.
- The sequential group required a mean of two injections.
- All patients had intrinsic sphincteric deficiency.
Conclusions:
- Sequential periurethral autologous fat injections may be more effective than single injections for treating SUI in women with ISD.
- The procedure warrants further investigation for selected SUI cases.