Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Innovations in pharmacologic therapies

C Miaskowski1

  • 1Department of Physiological Nursing, University of California, San Francisco 94143, USA.

Seminars in Oncology Nursing
|February 1, 1997
PubMed
Summary

Novel neurotransmitters offer new pain relief avenues. Research suggests NMDA antagonists and calcium channel blockers show promise for human analgesic trials, with further study needed for alpha 2 adrenergic agonists and GABA agonists.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unmet supportive care needs in prostate cancer survivors with advanced disease: A mixed-methods exploration.

Canadian oncology nursing journal = Revue canadienne de nursing oncologique·2024
Same author

Canadian oncology nursing journal = Revue canadienne de nursing oncologique·2024
Same author

The symptom phenotype of oncology outpatients remains relatively stable from prior to through 1 week following chemotherapy.

European journal of cancer care·2016
Same author

[Testing an intervention to support pain self management in oncologic patients: a mixed method pilot study].

Pflege·2012
Same author

Review article: self-report measures to evaluate constipation.

Alimentary pharmacology & therapeutics·2008
Same author

Factors influencing oral mucositis in patients receiving chemotherapy.

Cancer practice·2002

Area of Science:

  • Neuroscience
  • Pharmacology

Background:

  • Pain modulation involves complex neurotransmitter systems.
  • Emerging research identifies novel neurotransmitters with potential analgesic properties.

Purpose of the Study:

  • To elucidate the mechanism of action for four new neurotransmitters implicated in pain modulation.
  • To review the clinical implications of novel analgesic drug classes.

Main Methods:

  • Literature review encompassing research studies, proceedings, abstracts, and book chapters.
  • Focus on pharmacologic therapies for pain relief.

Main Results:

  • Advances in neurotransmitter and receptor physiology guide new analgesic development.
  • NMDA antagonists and calcium channel blockers are candidates for human investigation.

Conclusions:

  • Further human studies are required for alpha 2 adrenergic agonists and GABA agonists.
  • Understanding novel analgesics is crucial for targeted pain management strategies.

Related Experiment Videos