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Related Experiment Videos

Mortality trials with implantable defibrillators

S Nisam, G Breithardt

    The American Journal of Cardiology
    |February 15, 1997
    PubMed
    Summary
    This summary is machine-generated.

    Future clinical trials comparing antiarrhythmic drugs and implantable cardioverter-defibrillators face ethical challenges due to device efficacy. High-quality data from implantable cardioverter-defibrillators now enable drug efficacy studies without direct patient comparison.

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    Area of Science:

    • Cardiology
    • Clinical Trials
    • Medical Devices

    Background:

    • Recent studies show disappointing results with antiarrhythmic drugs for arrhythmias.
    • Implantable cardioverter-defibrillators demonstrate excellent long-term outcomes.
    • Ethical considerations impede direct comparison trials between drugs and devices.