[State of tissue-vascular permeability in diabetic patients with parodontosis]

The state of the parodontium was studied clinically and morphologically in 70 patients suffering from diabetes mellitus. Blood histamine and serotonin level was determined fluorometrically. Gingivitis was revealed in diabetic patients; the severity of inflammatory changes in the gingiva proved to depend on the duration and the severity of diabetes mellitus. Changes pointing to increase of the vaso-tissue permeability were revealed histologically. At the same time there was an increase in the blood histamine level and a tendency to reduction of serotonin level. This can serve as one of the factors causing an increase of the vascular permeability and a disturbance of microcirculation in the gingiva.