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Umbilical cord cysts in early pregnancy
J A Ross1, D Jurkovic, N Zosmer
1Academic Department of Obstetrics and Gynecology, King's College School of Medicine and Dentistry, University of London, United Kingdom.
Obstetrics and Gynecology
|March 1, 1997
Summary
Umbilical cord cysts are found in about 3% of first-trimester pregnancies. Over 20% of these cases show fetal abnormalities, with risks increasing if cysts persist or are located near cord extremities.
Area of Science:
- Perinatology
- Fetal Medicine
- Medical Ultrasound
Background:
- Umbilical cord cysts are uncommon findings during early pregnancy.
- Early detection of umbilical cord abnormalities is crucial for fetal well-being.
Purpose of the Study:
- To determine the prevalence of umbilical cord cysts in the first trimester.
- To characterize their morphology and natural history.
- To assess the association with fetal abnormalities.
Main Methods:
- Ultrasound screening of 859 pregnant women (7-13 weeks' gestation).
- Fortnightly follow-up scans for detected cysts.
- Detailed anomaly scans at 20 weeks and postnatal examination of infants and cords.
Main Results:
- Umbilical cord cysts detected in 3.4% of pregnancies.
- Fetal abnormalities occurred in 26% of ongoing pregnancies with cysts.
- Increased risk of fetal abnormality associated with cyst location and persistence beyond 12 weeks.
Conclusions:
- First-trimester umbilical cord cysts have a prevalence of approximately 3%.
- Over 20% of fetuses with umbilical cord cysts exhibit chromosomal or structural defects.
- Cyst characteristics can indicate increased risk for fetal anomalies.