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[Preliminary study on tuberculin sensitivity in north Lebanon]
1Université libanaise, Faculté de Santé publique, Section III, Tripoli, Liban.
Insights
Tuberculin sensitivity was investigated in 1,405 Lebanese school children. A 4.3% prevalence of tuberculosis infection was found, with higher rates in lower socio-economic groups and older children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Context:
- Tuberculosis (TB) poses a significant global health challenge, particularly impacting vulnerable populations.
- North Lebanon faces a substantial burden of childhood disease attributed to TB.
- This study focuses on a deprived suburb of Tripoli, Lebanon, to assess TB infection markers.
Purpose:
- To determine the prevalence of tuberculin sensitivity in school children in North Lebanon.
- To analyze the relationship between socio-economic status, age, sex, and tuberculin sensitivity.
- To evaluate the clinical status of children with positive tuberculin reactions.
Summary:
- A cross-sectional study assessed tuberculin sensitivity using the Intra-Dermal Reaction (IDR) technique in 1,405 BCG-unvaccinated school children (ages 2-15).
- The overall prevalence of tuberculin sensitivity was 4.3%, significantly higher in the lowest socio-economic group (5.7%) compared to the middle group (2.4%).
- Prevalence increased with age (over 10 years), and induration diameters exceeded 10 mm in 83.6% of positive cases. Chest X-rays and sputum tests for Acid Fast Bacilli (AFB) were negative in all children with positive reactions.
Impact:
- Highlights the significant prevalence of tuberculosis infection in school-aged children in a deprived area of North Lebanon.
- Identifies socio-economic status and age as key factors associated with higher tuberculin sensitivity.
- Suggests the need for targeted public health interventions and further investigation into latent tuberculosis infection in this population.
Abstract:
Tuberculosis remains a severe public health problem, and is a major cause of infant disease in North Lebanon. We investigated tuberculin sensitivity in 1,405 school children (2 to 15 years old) not previously vaccinated with BCG in a deprived suburb of Tripoli (Lebanon). The Intra-Dermal Reaction (IDR) technique was used with 10 units of tuberculin (Pasteur-Mérieux, France). The prevalence was 4.3%. The score was higher in the lowest socio-economic group (5.7%) than in the middle socio-economic group (2.4%). No members of the upper socio-demographic group live in this area. There were no significant differences between the sexes. The diameter of induration was over 10 mm in 83.6% of cases (95.6% in the lower class and 46.6% in the middle class). The prevalence was higher among children over 10 years old. Chest X-rays were obtained for children with a positive reaction, and all were normal. Similarly, their sputum was tested for Acid Fast Bacilli (AFB) by a double staining technique (Ziehl-Nielsen and auramine), and all scored negative.
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