Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Antidepressive treatment in general practice--an interview study]

J U Rosholm1, L F Gram, N Damsbo

  • 1Odense Universitet, Afdeling for Klinisk Farmakologi.

Ugeskrift for Laeger
|January 13, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pneumatic piston hydrostatic bioreactor for cartilage tissue engineering.

Instrumentation science & technology·2023
Same author

Non-vitamin K antagonist oral anticoagulants, proton pump inhibitors and gastrointestinal bleeds.

Heart (British Cardiac Society)·2021
Same author

Use of antipsychotics in Denmark 1997-2018: a nation-wide drug utilisation study with focus on off-label use and associated diagnoses.

Epidemiology and psychiatric sciences·2021
Same author

Baseline findings of the population-based, randomized, multifaceted Danish cardiovascular screening trial (DANCAVAS) of men aged 65-74 years.

The British journal of surgery·2019
Same author

The PARIS score can reliably predict 7-day all-cause mortality for both acute medical and surgical patients: an international validation study.

QJM : monthly journal of the Association of Physicians·2018
Same author

Association between use of phthalate-containing medication and semen quality among men in couples referred for assisted reproduction.

Human reproduction (Oxford, England)·2018
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

General practitioners often use antidepressants for extended periods, sometimes with uncertain indications, deviating from evidence-based guidelines. This practice may lead to suboptimal patient outcomes in managing depression.

Area of Science:

  • General Practice
  • Psychiatry
  • Pharmacology

Context:

  • Antidepressant use in general practice settings presents unique challenges.
  • Long-term treatment and varying indications are common.
  • Patient populations often exhibit significant depressive symptoms and functional impairment.

Purpose:

  • To investigate potential issues associated with antidepressant prescribing in general practice.
  • To evaluate the appropriateness and duration of antidepressant treatment.
  • To compare general practice prescribing patterns with evidence-based recommendations.

Summary:

  • A study interviewed 98 antidepressant users across 12 general practices.
  • Depression was the primary indication, with a median treatment duration of three years.

Related Experiment Videos

  • General practitioners found 23 cases problematic due to uncertain indication or alternative treatment considerations.
  • Modest side effects were reported, but patients often had high depression scores and poor functional status (WONCA-scale).
  • Key features included low doses, long treatment durations, and uncertainty regarding treatment relevance.

    • Impact:

    • Findings highlight a divergence between current antidepressant use in general practice and scientific recommendations.
    • Identifies areas for improved guideline adherence and patient care in primary mental healthcare.
    • Suggests a need for better diagnostic clarity and treatment evaluation for antidepressants in primary care settings.