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Reevaluation of postoperative radiotherapy for thoracic esophageal carcinoma
M Yamamoto1, T Yamashita, T Matsubara
1Department of Radiology, Cancer Institute Hospital, Tokyo, Japan.
Purpose:
To reevaluate postoperative radiotherapy for thoracic esophageal carcinoma.
Methods And Materials:
Reviewed were the outcome of 89 patients who underwent esophagectomy with systematic dissection of regional lymph nodes between 1988 and 1993. Of the 89 patients, 19 underwent no adjuvant treatment, 22 underwent adjuvant chemotherapy alone, and 48 underwent postoperative radiotherapy. Twelve of the 48 also underwent adjuvant chemotherapy.
Results:
All patients who experienced local-regional recurrence had lymph node metastases at the time of surgery. The actuarial local-regional control rate at 2-year of follow-up was 94% for patients with lymph node metastases at the time of surgery who underwent postoperative radiotherapy alone or plus chemotherapy, and 74% for those who underwent adjuvant chemotherapy alone. The local-regional control rate was significantly better for those who had undergone postoperative radiotherapy (p < 0.01).
Conclusions:
Postoperative radiotherapy still plays an important role as adjuvant treatment.
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