Related Experiment Video
Updated: Aug 19, 2026

Assay for Neural Induction in the Chick Embryo
Published on: February 13, 2009
Vertebrate neural induction
A Hemmati-Brivanlou1, D Melton
1Center for Neurosciences, The Rockefeller University, New York, New York 10021-6399, USA.
Abstract:
During early vertebrate development, the cells of the ectoderm choose between two possible fates: neural and epidermal. The process of neural induction was discovered nearly 70 years ago in vertebrates, and molecular analyses in recent years using Xenopus laevis embryos have identified several secreted factors with direct neural-inducing ability. There is considerable evidence that the mechanism of neuralization by these inducing factors is under inhibitory control and involves derepression. This review focuses on factors involved in the specification of neural fate within the frame of the default model of neural induction.
Related Concept Videos
Neurulation
Determination

