Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal abnormalities in ankylosing spondylitis

M J Vilar1, S E Cury, M B Ferraz

  • 1Department of Medicine, Escola Paulista de Medicina (UNIFESP), São Paulo, Brazil.

Scandinavian Journal of Rheumatology
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dry cow therapy and early lactation udder health problems-Associations and risk factors.

Preventive veterinary medicine·2021
Same author

Dry-off and dairy cow udder health and welfare: Effects of different milk cessation methods.

Veterinary journal (London, England : 1997)·2020
Same author

Antibiotic dry cow therapy, somatic cell count, and milk production: Retrospective analysis of the associations in dairy herd recording data using multilevel growth models.

Preventive veterinary medicine·2020
Same author

Initial renal histology and early response predict outcomes of Brazilian lupus nephritis patients.

Lupus·2019
Same author

Short communication: Drying-off practices and use of dry cow therapy in Finnish dairy herds.

Journal of dairy science·2018
Same author

Revisiting an unsolved problem - impact of SLICC criteria on the risk of metabolic syndrome.

Lupus·2016

Ankylosing Spondylitis (AS) patients frequently show kidney problems, including hematuria and reduced renal function. Early screening for renal dysfunction in AS patients is recommended.

Area of Science:

  • Nephrology
  • Rheumatology
  • Immunology

Background:

  • Renal abnormalities are noted in Ankylosing Spondylitis (AS).
  • Potential causes include NSAID use, glomerulonephritis, and amyloidosis.
  • The exact frequency and type of kidney dysfunction in AS require further investigation.

Purpose of the Study:

  • To assess the frequency and severity of renal dysfunction in AS patients.
  • To utilize sensitive tests for glomerular and tubular function.
  • To identify specific markers of kidney involvement in this cohort.

Main Methods:

  • Prospective evaluation of 40 consecutive AS patients.
  • Utilized sensitive tests for glomerular and tubular function.
  • Assessed parameters including serum creatinine, creatinine clearance, and urinalysis for hematuria and microalbuminuria.

Related Experiment Videos

Main Results:

  • 14 out of 40 AS patients (35%) exhibited renal abnormalities.
  • Microscopic hematuria was observed in 9 patients.
  • Microalbuminuria, decreased serum creatinine, and reduced creatinine clearance were noted in 4, 2, and 4 patients, respectively.
  • No patients showed increased urinary retinol binding protein (RBP) excretion.

Conclusions:

  • A significant percentage of AS patients present with renal involvement.
  • Kidney dysfunction in AS can manifest as hematuria, microalbuminuria, and impaired renal function.
  • Active investigation for renal abnormalities is crucial in managing Ankylosing Spondylitis patients.