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Related Experiment Videos

Cesarean delivery. Microbial colonization in amniotic fluid

L Keski-Nisula1, P Kirkinen, M L Katila

  • 1Department of Obstetrics and Gynecology, Kuopio University Hospital, Finland.

The Journal of Reproductive Medicine
|February 1, 1997
PubMed
Summary

Intra-amniotic microbial colonization is common during cesarean delivery, particularly with ruptured membranes. However, this invasion has low clinical significance for maternal infection risk.

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Microbiology

Background:

  • Intra-amniotic microbial colonization can occur in pregnant individuals without clinical signs of infection.
  • Understanding the prevalence and impact of this colonization is crucial for patient care during cesarean delivery.

Purpose of the Study:

  • To investigate the frequency of intra-amniotic microbial colonization.
  • To assess its clinical significance in uninfected women undergoing cesarean delivery.
  • To identify causative factors associated with this colonization.

Main Methods:

  • Amniotic fluid samples were collected via direct aspiration during cesarean sections from 251 pregnant women.
  • Bacterial and mycoplasmal cultures were performed on the samples.

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  • Postoperative maternal infection symptoms were monitored for one week.

    • Main Results:

    • Microbial invasion of amniotic fluid was found in 29% of patients, significantly higher in those with ruptured membranes (66%).
    • Ureaplasma urealyticum, Lactobacillus species, and coagulase-negative staphylococci were the most common isolates.
    • Internal monitoring before surgery was the sole significant risk factor for colonization in women with ruptured membranes.

    Conclusions:

    • Despite a high incidence, intra-amniotic microbial invasion showed low clinical significance regarding maternal puerperal morbidity.
    • Internal monitoring during labor is identified as a key risk factor for amniotic fluid microbial colonization in specific patient groups.