Apoptosis and the dilemma of cancer chemotherapy

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment.

Oncogene·2017

Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system.

Cell death & disease·2016

P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest.

Cell death & disease·2015

Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid.

Oncogene·2015

Defining a role for sphingosine kinase 1 in p53-dependent tumors.

Oncogene·2011

Ceramide and the regulation of apoptosis and the stress response.

Trends in cardiovascular medicine·2011

DMT1 Facilitates Heme-iron Absorption in Rats and Mice.

Blood·2026

New FDA-Approved Treg Therapy to Reduce Chronic GVHD After Allogeneic HSCT.

Blood·2026

Pembrolizumab-GVD in relapsed or refractory Hodgkin lymphoma: 5-year update of a multicenter phase 2 trial.

Blood·2026

Enhanced factor VIII activation accelerates thrombin generation and hemostatic potency in mice.

Blood·2026

--Paneth cell niche function is critical for intestinal stem cells in radiation injury but dispensable in GVHD.

Blood·2026

Inhibition of mitochondrial permeability transition selectively suppresses thrombogenic platelet procoagulant activity.

Blood·2026

Preclinical mechanistic study of rotundic acid against cyclophosphamide-induced nephrotoxicity in Swiss albino mice through modulation of oxidative stress, inflammation, apoptosis, and fibrosis via NF-κB/Caspase-3/TGF-β1 Pathways.

Biochemical and biophysical research communications·2026

Biological effects of N-acetylcysteine, calcium hydroxide, chlorhexidine and their combinations as intracanal medications: cytotoxicity, genotoxicity and cytokine modulation.

BDJ open·2026

Clinical Determinants Influencing First-line Immune Checkpoint Inhibitor Selection for Unresectable Hepatocellular Carcinoma in Japan.

Anticancer research·2026

Comparing the real-world effectiveness of oral corticosteroids and antifungals for the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis.

Chest·2026

Unravelling the synergistic potential of Olibanum extract and Bacillus clausii in combating intestinal cryptosporidiosis in immunosuppressed mice.

PLoS neglected tropical diseases·2026

Bifunctional Nanozymes for Synergistic Treatment by Boosting Oxidative Stress and Regulating the Protein Kinase B Pathway.

ACS nano·2026

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Apoptosis and the dilemma of cancer chemotherapy

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P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment.

Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system.

P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest.

Ceramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipid.

Defining a role for sphingosine kinase 1 in p53-dependent tumors.

Ceramide and the regulation of apoptosis and the stress response.

DMT1 Facilitates Heme-iron Absorption in Rats and Mice.

New FDA-Approved Treg Therapy to Reduce Chronic GVHD After Allogeneic HSCT.

Pembrolizumab-GVD in relapsed or refractory Hodgkin lymphoma: 5-year update of a multicenter phase 2 trial.

Enhanced factor VIII activation accelerates thrombin generation and hemostatic potency in mice.

--Paneth cell niche function is critical for intestinal stem cells in radiation injury but dispensable in GVHD.

Inhibition of mitochondrial permeability transition selectively suppresses thrombogenic platelet procoagulant activity.

Preclinical mechanistic study of rotundic acid against cyclophosphamide-induced nephrotoxicity in Swiss albino mice through modulation of oxidative stress, inflammation, apoptosis, and fibrosis via NF-κB/Caspase-3/TGF-β1 Pathways.

Biological effects of N-acetylcysteine, calcium hydroxide, chlorhexidine and their combinations as intracanal medications: cytotoxicity, genotoxicity and cytokine modulation.

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