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Moyamoya disease in Brazil
C Minelli1, O M Takayanagui, A C dos Santos
1Department of Neurology, Faculty of Medicine of Ribeiräo Preto, University of São Paulo, Brazil.
Acta Neurologica Scandinavica
|February 1, 1997
Summary
Moyamoya disease, a rare cerebrovascular disorder, is increasingly reported globally. This study highlights its underestimation in Brazil, with only two of six previously reported cases meeting diagnostic criteria.
Area of Science:
- Neurology
- Vascular Neurology
- Epidemiology
Background:
- Moyamoya disease, initially thought to be geographically restricted, is now recognized worldwide.
- This study presents seven new cases from Brazil and reviews existing literature.
Purpose of the Study:
- To investigate the prevalence and diagnostic accuracy of moyamoya disease in Brazil.
- To compare reported cases with established diagnostic criteria.
Main Methods:
- Diagnosis was confirmed using the criteria set by the Research Committee on Spontaneous Occlusion of the Circle of Willis.
- A review and meta-analysis of previously reported Brazilian cases were conducted.
Main Results:
- Of the seven new cases, five experienced ischemic events and two had hemorrhagic events.
- A meta-analysis revealed that only two of six previously reported cases met the strict diagnostic criteria for moyamoya disease.
Conclusions:
- The true incidence of moyamoya disease in Brazil is likely underestimated.
- Accurate diagnosis based on established criteria is crucial for understanding the disease's epidemiology.