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International opioid consumption

T G Clausen1

  • 1Multidisciplinary Pain Center, National University Hospital, Rigshospitalet, Copenhagen, Denmark.

Acta Anaesthesiologica Scandinavica
|January 1, 1997
PubMed
Summary
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Danish opioid consumption dramatically increased by 353% between 1981 and 1993, reaching the world

Area of Science:

  • Pain Management
  • Pharmacology
  • Public Health

Background:

  • Opioid consumption has seen a global increase.
  • Understanding consumption patterns is crucial for public health.
  • Denmark's opioid use warrants comparative analysis.

Purpose of the Study:

  • To analyze opioid consumption in the top 10 consuming countries.
  • To compare these with Danish opioid consumption patterns.
  • To investigate the indications for opioid prescriptions in Denmark.

Main Methods:

  • Comparative analysis of opioid consumption data from 10 countries and Denmark.
  • Examination of prescription data for opioid use in Denmark.
  • Calculation of defined daily doses (DDD) per 1 million inhabitants.

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Main Results:

  • Total opioid consumption rose significantly (26-1423%) in the 10 highest-consuming nations.
  • Danish opioid consumption surged by 353% (1981-1993), reaching over 1.45 million DDD/million inhabitants in 1993.
  • Morphine, methadone, ketobemidone, and buprenorphine were the primary opioids consumed in Denmark.
  • Long-acting opioid consumption increased by 1427%, while short-acting increased by 105%.
  • Less than 10% of general practitioner opioid prescriptions were for cancer pain.

Conclusions:

  • Denmark exhibits the highest per capita opioid consumption globally.
  • The pattern of Danish opioid use, particularly the high volume, is notable.
  • While Denmark's cancer pain management may be a model, its overall high opioid consumption requires attention.