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Oral or vaginal misoprostol for induction of labor
M K Toppozada1, M Y Anwar, H A Hassan
1Department of Obstetrics and Gynecology, University of Alexandria, Egypt.
Objective:
To compare vaginal versus oral misoprostol for induction of labor.
Method:
Induction of labor was carried out in 40 women near term in two equal and randomized groups (according to a computer generated table) using misoprostol. Group I received vaginal misoprostol (100 micrograms) every 3 h while group II patients were given the same dose via the oral route. The dose was doubled if no response was detected under continuous cardiotocographic (CTG) tracings.
Result:
The vaginal route of administration induced a higher success rate in a shorter time interval using a lower dose but was associated with more abnormal FHR patterns and instances of uterine hyperstimulation.
Conclusion:
It is recommended to use the vaginal approach with cardiotocographic monitoring.
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