Ultrastructural aspects of hair digestion in black piedra infection
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M J Figueras1, J Guarro, L Zaror
1Unitat de Microbiologia, Facultat de Medicino i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Espanya.
Abstract:
The ultrastructural pattern of human hair infection by Piedraia hortae in vivo has been studied. The fungus destroyed the cuticular layers of the hair and was able to penetrate deeply into the cortex. The course of destruction of human hair is described and compared with that produced by other fungi. Two well-defined types of cortex digestion were characterized. The slow rate of keratin degradation at the cortex together with the compacted stromatic organization of the nodules are argued as the main reasons that guarantee the long survival of the fungus, and therefore the chronic course of the disease. The data provided in this paper may help to understand the mechanisms that regulate the pathogenicity of this fungus.
Insights
Piedraia hortae fungus destroys human hair by penetrating the cuticle and cortex. Slow keratin digestion and nodule structure explain the chronic infection course.
Area of Science:
- Mycology
- Dermatology
- Pathology
Background:
- Human hair infections can be caused by various fungi.
- Piedraia hortae is a fungus known to cause black piedra, a hair infection.
Purpose of the Study:
- To investigate the ultrastructural pattern of human hair infection by Piedraia hortae in vivo.
- To understand the mechanisms of hair destruction and fungal survival.
Main Methods:
- Ultrastructural analysis of infected human hair.
- Microscopic examination of fungal invasion and hair degradation.
Main Results:
- Piedraia hortae destroys hair cuticle and penetrates deep into the cortex.
- Two distinct types of cortex digestion were identified.
- Slow keratin degradation and compacted nodule structure contribute to fungal survival.
Conclusions:
- The study elucidates the pathogenesis of Piedraia hortae infection in human hair.
- Understanding these mechanisms may aid in managing chronic hair infections.