Related Experiment Videos
Subretinal aspiration biopsy of ocular lymphoma
T A Ciulla1, R D Pesavento, S Yoo
1Department of Ophthalmology, Indiana University School of Medicine, USA.
Purpose:
Large-cell lymphoma can be difficult to diagnose because vitreous biopsies may fail to disclose neoplastic cells.
Methods:
We report one such case in which diagnosis was confirmed by subretinal aspiration of yellow-white infiltrates using a pars plana approach.
Results:
A 67-year-old woman with recurrent bilateral uveitis was diagnosed with large-cell lymphoma by subretinal aspiration of yellow-white infiltrates after two vitreous biopsies and a concurrent retinal biopsy failed to confirm the diagnosis.
Conclusions:
When the suspicion of intraocular lymphoma remains high despite previous negative vitreous biopsies, retinal biopsy and aspiration biopsy of subretinal lesions may enhance the diagnostic yield.