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[Abnormal T cell maturation in myasthenia gravis associated thymomas]
R Nenninger1, A Schultz, H K Müller-Hermelink
1Institut für Pathologie, Universität Würzburg.
Verhandlungen Der Deutschen Gesellschaft Fur Pathologie
|January 1, 1996
Summary
Thymoma subtypes show distinct T cell maturation defects. Medullary thymomas may cause autoimmunity via T cell activation, while cortical and mixed thymomas contribute through abnormal T cell selection in myasthenia gravis pathogenesis.
Area of Science:
- Immunology
- Autoimmunity
- T cell biology