Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperemesis gravidarum: is serotonin implicated?

A Borgeat1, M Fathi, A Valiton

  • 1Department of Anesthesiology, Geneva University Hospital, Switzerland.

American Journal of Obstetrics and Gynecology
|February 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Curcumin and nano-curcumin applications in psychiatric disorders.

Phytotherapy research : PTR·2024
Same author

Swimming exercise and clove oil can improve memory by molecular responses modification and reduce dark cells in rat model of Alzheimer's disease.

Experimental gerontology·2023
Same author

Effects of an specific methodology (I Pass the Baton) on quality of handoff information among Nurses: A comparative study.

Journal of healthcare quality research·2022
Same author

Flu and pertussis vaccination during pregnancy in Geneva during the COVID-19 pandemic: A multicentric, prospective, survey-based study.

Vaccine·2022
Same author

The effects of Alzheimer's and Parkinson's disease on 28-day mortality of COVID-19.

Revue neurologique·2021
Same author

[Hepatitis B Virus (Hepadnaviridae: Orthohepadnavirus: Hepatitis B virus) among Hospitalized Mentally Disabled Patients is not transmitted by their nurses or family members].

Voprosy virusologii·2021

This study investigated serotonin excretion in hyperemesis gravidarum. Results show no significant difference in urinary hydroxyindoleacetic acid, indicating serotonin secretion is not increased in this condition.

Area of Science:

  • Reproductive biology
  • Biochemistry
  • Medical research

Background:

  • Hyperemesis gravidarum is a severe pregnancy complication characterized by nausea and vomiting.
  • The role of serotonin in the pathophysiology of hyperemesis gravidarum remains unclear.
  • Previous research suggests potential links between neurotransmitters and pregnancy-related nausea.

Purpose of the Study:

  • To investigate serotonin excretion in women experiencing hyperemesis gravidarum.
  • To determine if increased serotonin secretion is associated with hyperemesis gravidarum.
  • To compare serotonin metabolite levels between different groups of women.

Main Methods:

  • Urinary hydroxyindoleacetic acid (a serotonin metabolite) was measured.
  • Three groups were studied: women with hyperemesis gravidarum, pregnant women without nausea/vomiting, and non-pregnant women.

Related Experiment Videos

  • Standardized urine collection and assay techniques were employed.

    • Main Results:

    • No significant differences were observed in urinary hydroxyindoleacetic acid excretion among the three groups.
    • The data did not support an elevated serotonin secretion in women with hyperemesis gravidarum.
    • Individual variations in excretion levels were noted but did not reach statistical significance between groups.

    Conclusions:

    • Hyperemesis gravidarum is not associated with increased serotonin secretion.
    • Serotonin pathways may not be a primary driver of hyperemesis gravidarum.
    • Further research into other potential etiological factors is warranted.