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Updated: Aug 21, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
Published on: April 7, 2017
Malignant cystosarcoma phyllodes tumor of the breast mainly composed of chondrosarcoma: a case report
K Iihara1, R Machinami, S Kubota
1Department of Pathology, Toshiba Hospital, Tokyo, Japan.
Abstract:
Sarcoma of the breast is a very rare occurrence. We experienced a patient with malignant phyllodes tumor, in which a chondrosarcomatous element constituted 90% of the tumor volume. That bone or cartilage may be present in mammary neoplasms has been known for a long time. Most mammary tumors with areas of chondroid metaplasia show a benign histologic appearance. Cystosarcoma phyllodes displaying a chondrosarcomatous element is very rare. The results obtained by echographic and pathologic examinations strongly suggest that the chondrosarcomatous element originates from the fibrous stroma.

