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Systemic immediate-type reactions to gelatin included in Japanese encephalitis vaccines
M Sakaguchi1, M Yoshida, W Kuroda
1Department of Epidemiology, National Institute of Health, Tokyo, Japan.
Vaccine
|February 1, 1997
Abstract:
Three children had systemic immediate-type reactions to Japanese encephalitis (JE) vaccine which contains gelatin as a stabilizer. We found that all the children had anti-gelatin IgE in their sera. Further, two of the three also had experienced systemic allergic reactions to gelatin-containing foods before the vaccination. We assume that the systemic allergic reactions to JE vaccines might be caused by gelatin in the JE vaccine.