Related Experiment Video
Updated: Aug 9, 2026

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
Published on: October 22, 2013
Intracellular Campylobacter-like organisms associated with rectal prolapse and proliferative enteroproctitis in emus
T X Lemarchand1, T N Tully, S M Shane
1Department of Pathology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.
Abstract:
Rectal prolapse was the presenting clinical finding in a group of juvenile emus (Dromaius novaehollandiae). Gross findings included severely thickened and rugose distal rectal mucosae. Histologically, there were thickened villi, enterocyte hyperplasia, dilated glands filled with mucus and heterophils, and a dense infiltrate of heterophils, macrophages, lymphocytes, and plasma cells in the lamina propria. Examination of Warthin-Starry silver-stained sections revealed numerous apically located comma-shaped intracytoplasmic bacteria approximately 1 x 3 microns in size. Campylobacter-like organisms morphologically compatible with ileal symbiont intracellularis now known as Lawsonia intracellularis were seen via electron microscopy. Bacteria were further characterized by indirect immunofluorescence using monoclonal antibody specific for the 25-27-kd outer membrane protein of L. intracellularis.
Related Concept Videos
Bacterial Phylum Chlamydiae
Diversity of Protists I
Colonisation of Pathogens
Bacterial Gastroenteritis
Giardiasis
Amebiasis

