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Related Experiment Videos

Drug-induced hiccups

D F Thompson1, J P Landry

  • 1Department of Pharmacy Practice, School of Pharmacy, Southwestern Oklahoma State University, Weatherford 73096, USA.

The Annals of Pharmacotherapy
|March 1, 1997
PubMed
Summary
This summary is machine-generated.

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Drug-induced hiccups are rare, with corticosteroids and benzodiazepines most frequently cited. However, current evidence is insufficient to definitively link any specific medication to causing hiccups.

Area of Science:

  • Pharmacology
  • Neurology
  • Clinical Medicine

Background:

  • Hiccups are involuntary diaphragmatic spasms.
  • Pharmacotherapeutic agents are rarely implicated in hiccup etiology.
  • Corticosteroids and benzodiazepines are frequently mentioned in literature reviews concerning drug-induced hiccups.

Purpose of the Study:

  • To evaluate the association between pharmacotherapeutic agents and hiccups.
  • To determine if sufficient evidence exists to classify any drug as causative for hiccups.

Main Methods:

  • Literature review of studies reporting drug-associated hiccups.
  • Critical analysis of evidence using strict criteria for causality.

Main Results:

Related Experiment Videos

  • Pharmacotherapeutic agents are uncommonly associated with hiccups.
  • Corticosteroids and benzodiazepines are the most frequently reported drug classes.
  • Insufficient evidence exists to establish any drug as a definitive cause of hiccups.

    • Conclusions:

    • While certain drugs like corticosteroids and benzodiazepines are frequently reported, a causal link to hiccups remains unproven.
    • Further rigorous research is needed to establish definitive drug causality for hiccups.