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Biliary tract obstruction due to sarcoidosis: a case report
1King Faisal Specialist Hospital and Research Centre, Department of Medicine, Riyadh, Kingdom of Saudi Arabia.
The American Journal of Gastroenterology
|March 1, 1997
Summary
A rare case of hepatic sarcoidosis mimicked bile duct cancer, causing jaundice. Treatment with corticosteroids successfully relieved the biliary obstruction.
Area of Science:
- Hepatology
- Immunology
- Gastroenterology
Background:
- Cholestatic jaundice can present with diverse etiologies, necessitating thorough differential diagnosis.
- Cholangiocarcinoma is a significant concern in patients with obstructive jaundice.
Observation:
- A 43-year-old male presented with cholestatic jaundice.
- Endoscopic retrograde cholangiopancreatography (ERCP) findings suggested cholangiocarcinoma.
- Liver biopsy revealed non-caseating granulomas, atypical for malignancy.
Findings:
- The patient was diagnosed with hepatic sarcoidosis presenting as biliary tract obstruction.
- Non-caseating granulomas on liver biopsy are characteristic of sarcoidosis.
Implications:
- Hepatic sarcoidosis can uncommonly manifest as biliary obstruction, mimicking malignancy.
- Corticosteroid therapy proved effective in resolving the biliary obstruction caused by sarcoidosis.