Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DNA: Insulator or wire?

D N Beratan1, S Priyadarshy, S M Risser

  • 1Department of Chemistry, University of Pittsburgh, PA 15260, USA.

Chemistry & Biology
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Universal free-energy landscape produces efficient and reversible electron bifurcation.

Proceedings of the National Academy of Sciences of the United States of America·2020
Same author

DNA charge transfer: Hot holes break the speed limit.

Nature chemistry·2016
Same author

Vibrational control of electron-transfer reactions: a feasibility study for the fast coherent transfer regime.

Physical chemistry chemical physics : PCCP·2015
Same author

Electron tunneling pathways in proteins: influences on the transfer rate.

Photosynthesis research·2014
Same author

Simulation of scanning tunneling microscope images of 1,3-cyclohexadiene bound to a silicon surface.

The journal of physical chemistry. B·2006
Same author

Determining absolute configuration in flexible molecules: a case study.

Journal of the American Chemical Society·2001
Same journal

The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation.

Chemistry & biology·2017
Same journal

DIVERSE System: De Novo Creation of Peptide Tags for Non-enzymatic Covalent Labeling by In Vitro Evolution for Protein Imaging Inside Living Cells.

Chemistry & biology·2015
Same journal

Differential Regulation of Specific Sphingolipids in Colon Cancer Cells during Staurosporine-Induced Apoptosis.

Chemistry & biology·2015
Same journal

Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Iα.

Chemistry & biology·2015
Same journal

Unraveling the B. pseudomallei Heptokinase WcbL: From Structure to Drug Discovery.

Chemistry & biology·2015
Same journal

Vitamin C as Cancer Destroyer, Investigating Sulfhydration, and the Variability in CFTR Interactome.

Chemistry & biology·2015
See all related articles

Understanding electron transfer in DNA is key for biosynthesis and radiation repair. Experiments and theory can reveal electron travel distance and speed within DNA molecules.

Area of Science:

  • Biophysics
  • Molecular Biology
  • Biochemistry

Background:

  • DNA-mediated electron transfer is crucial for biological processes like DNA repair and biosynthesis.
  • The precise mechanisms, distances, and timescales of electron transport in DNA remain poorly understood.
  • Understanding these processes is vital for fields ranging from medicine to nanotechnology.

Purpose of the Study:

  • To explore experimental approaches for measuring electron transfer rates and distances in DNA.
  • To investigate the predictions of modern theoretical models regarding DNA electron transport.
  • To elucidate the fundamental principles governing electron mobility within DNA structures.

Main Methods:

  • Propose experimental techniques such as time-resolved spectroscopy and electrochemical methods.

Related Experiment Videos

  • Discuss theoretical frameworks including quantum mechanical calculations and molecular dynamics simulations.
  • Consider studies on DNA-modified electrodes and DNA-templated nanostructures.

    • Main Results:

    • Electron transfer in DNA can occur over significant distances, influenced by DNA sequence and structure.
    • Theoretical models predict varying electron transfer rates dependent on molecular architecture and environmental factors.
    • Experimental data can provide insights into the dynamics and pathways of charge transport.

    Conclusions:

    • A combination of advanced experimental techniques and sophisticated theoretical modeling is necessary to fully understand DNA electron transfer.
    • Further research will clarify the roles of DNA structure and environment in modulating electron transport efficiency.
    • Elucidating these mechanisms could lead to novel applications in DNA-based electronics and therapeutics.