Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Corneal temperature changes during photorefractive keratectomy

S Betney1, P B Morgan, S J Doyle

  • 1Department of Optometry and Vision Sciences, University of Manchester Institute of Science and Technology, England.

Cornea
|March 1, 1997
PubMed
Summary

Photorefractive keratectomy (PRK) can significantly increase corneal temperature, potentially reaching levels that denature collagen and cause subepithelial haze. This study quantified temperature changes during PRK, highlighting the need for strategies to mitigate thermal effects.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Latent autoimmune diabetes of adulthood (LADA) is associated with small fibre neuropathy.

Diabetic medicine : a journal of the British Diabetic Association·2018
Same author

Coincident molecular auxeticity and negative order parameter in a liquid crystal elastomer.

Nature communications·2018
Same author

Flame exposure time on Langmuir probe degradation, ion density, and thermionic emission for flame temperature.

The Review of scientific instruments·2017
Same author

Use of thermocouples and argon line broadening for gas temperature measurement in a radio frequency atmospheric microplasma jet.

The Review of scientific instruments·2017
Same author

Graphene electrodes for adaptive liquid crystal contact lenses.

Optics express·2016
Same author

Field-induced refractive index variation in the dark conglomerate phase for polarization-independent switchable liquid crystal lenses.

Applied optics·2014

Area of Science:

  • Ophthalmology
  • Laser eye surgery
  • Corneal physiology

Background:

  • Subepithelial haze after photorefractive keratectomy (PRK) is a known complication.
  • Corneal temperature elevation during PRK is suspected to contribute to haze formation.
  • Quantifying intraoperative corneal temperature changes is crucial for understanding haze aetiology.

Purpose of the Study:

  • To precisely measure and quantify the temperature fluctuations on the ocular surface during PRK.
  • To investigate the relationship between PRK parameters and corneal temperature elevation.
  • To provide data for developing strategies to minimize thermal damage during PRK.

Main Methods:

  • Utilized non-contact, color-coded ocular thermography with an infrared detection system.

Related Experiment Videos

  • Monitored corneal temperature in 12 subjects undergoing PRK.
  • Recorded temperature changes throughout the surgical procedure.

    • Main Results:

    • The mean central ocular surface temperature (OST) post-epithelial debridement was 29.15°C.
    • The mean peak OST during PRK reached 37.77°C, with rapid increases within the first 15 seconds.
    • Ablation depth, optical correction, and procedure duration did not significantly correlate with temperature changes, indicating a complex interplay.

    Conclusions:

    • Corneal temperatures during routine PRK can approach the denaturation point of corneal collagen (approximately 39°C).
    • The findings support the hypothesis that thermal effects during PRK contribute to subepithelial haze.
    • Further research into preoperative cooling and treatment pauses is recommended to mitigate temperature-related complications.