[Ultrastructural changes in the hemato-testicular barrier in the pathogenesis of infertility]

An ejaculate and biopsy specimen of the testes from 162 patients with infertility of different etiology were studied. General regularities were established of development of pathospermy on the ultrastructural level in diseases of urogenital genesis. Development of infertility appear to be conditioned by consecutive interrelated processes of changes in the structure of different components of the hemato-testicular barrier. Changes in the capillary structure and primary with respect to disorders in other elements of the hemato-testicular barrier. Changes in the germinal system appear to occur secondary to the trophic abnormalities. In the hemomicrocirculatory bed of the testes, structural changes were at their greatest in the venular link.