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[Perinatal morbimortality associated with placental senescence]
G Romero-Gutiérrez1, R González-Ramos, M A Valadez-Ortega
1Instituto Mexicano del Seguro Social, Hospital de Gineco-Obstetricia, Centro Médico León, Guanajuato.
Ginecologia Y Obstetricia De Mexico
|January 1, 1997
Summary
Placental senescence (grade III placenta) is linked to adverse pregnancy outcomes like oligohydramnios and non-reactive tests. Closer monitoring of these pregnancies is recommended to improve neonatal outcomes.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Fetal Development
Background:
- Placental grading is used to assess fetal well-being.
- Placental senescence, indicated by grade III changes, may impact pregnancy outcomes.
Purpose of the Study:
- To evaluate the association between placenta grade III changes and neonatal outcomes.
- To determine if placental senescence affects perinatal morbidity.
Main Methods:
- Prospective study involving 370 patients.
- Case group: 182 patients with placenta grade III (senescence).
- Control group: 188 patients with placenta grade 0, I, or II.
Main Results:
- Grade III placenta associated with oligohydramnios (37% vs 24%), non-reactive cardiotocography (35 vs 17), and higher C-section rates (83%).
- Newborns showed no difference in birth weight or Apgar scores.
- Placental senescence linked to increased meconium-stained fluid (13% vs 8%) and special care nursery admissions (17 vs 5).
Conclusions:
- Placental senescence is closely associated with increased perinatal morbidity.
- Enhanced surveillance for pregnancies with placental grade III changes is suggested to improve perinatal outcomes.