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Elimination of plasmids from several bacterial species by novobiocin

G L McHugh, M N Swartz

Antimicrobial Agents and Chemotherapy

|September 1, 1977

Abstract:

Certain plasmids can be eliminated by exposure to growth-inhibiting concentrations of novobiocin. Novobiocin cured 8 of 14 plasmids (13 R-plasmids and an F' lac) among one or another of four different bacterial hosts.

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