Uptake and distribution of cadmium in mice following repeated administrations

The research was undertaken to analyze the uptake and distribution of cadmium-109 in mice following repeated injections and to observe how the simultaneous administrations of zinc affected the cadmium retention. Mice were given one, two, or three intravenous administrations at 48-hr intervals. Animals were sacrificed 2 min to 48 hr after each injection. Zinc had little effect on the retention of cadmium in the samples analyzed, and injections behaved independently of each other.