Related Experiment Video
Updated: Aug 11, 2026
11:40
Quantitative Autonomic Testing
Published on: July 19, 2011
Patterns of sympathetic skin response in palmar hyperhidrosis
Summary
Sympathetic skin responses (SSRs) in palmar hyperhidrosis vary based on palm temperature and moisture. These variations influence the types of SSRs observed, impacting diagnosis and understanding of the condition.
Area of Science:
- Neurology
- Dermatology
- Physiology
Background:
- Palmar hyperhidrosis is characterized by excessive sweating of the palms.
- Sympathetic skin responses (SSRs) are a key indicator of sympathetic nervous system function.
- Understanding SSR variations in palmar hyperhidrosis is crucial for diagnosis.
Purpose of the Study:
- To investigate the characteristics of sympathetic skin responses (SSRs) in patients with palmar hyperhidrosis.
- To determine the relationship between palmar skin conditions (temperature, moisture) and SSR patterns.
- To identify different types of SSRs and their prevalence in palmar hyperhidrosis.
Main Methods:
- Studied 44 patients diagnosed with palmar hyperhidrosis.
- Evoked palmar SSRs using median nerve stimulation and magnetic neck stimulation.
- Classified SSRs into four types: normal, small-amplitude, multiphasic, and absent.
- Categorized palmar conditions into warm-wet, warm-dry, cold-wet, and cold-dry.
Main Results:
- Identified four distinct SSR types and four palmar conditions.
- Normal SSRs were found in approximately 25% of patients, absent SSRs in another 25%.
- Patients with cold-dry palms exclusively exhibited absent SSRs, suggesting a strong correlation.
Conclusions:
- Palm skin temperature and moisture significantly influence the types of SSRs observed in palmar hyperhidrosis.
- The findings suggest that SSR patterns can be modulated by the local palmar environment.
- Further research into these correlations may refine diagnostic approaches for hyperhidrosis.
More Related Videos
Related Concept Videos
01:25The Sympathetic Nervous System
Overview
01:16Sensory Functions of the Skin
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
01:16Accessory Structures of the Skin: Hair and Hair Follicles
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
01:20Accessory Structures of the Skin: Sweat Glands
Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products.
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...
01:16Sympathetic Activation
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
01:27Assessment of the Cardiovascular System III: Palpation
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...