Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Case-control studies and their application to endocrinology

E B Gold1

  • 1Department of Epidemiology and Preventive Medicine, University of California, Davis, USA.

Endocrinology and Metabolism Clinics of North America
|March 1, 1997
PubMed
Summary

This guide details the case-control study approach for identifying disease causes, emphasizing proper methods and avoiding biases. It covers case/control selection, exposure assessment, sample size, data analysis, and causality assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Age at menarche and risk of vasomotor menopausal symptoms: a pooled analysis of six studies.

BJOG : an international journal of obstetrics and gynaecology·2020
Same author

Bleeding patterns during the menopausal transition in the multi-ethnic Study of Women's Health Across the Nation (SWAN): a prospective cohort study.

BJOG : an international journal of obstetrics and gynaecology·2014
Same author

Indoor carbon monoxide and PM2.5 concentrations by cooking fuels in Pakistan.

Indoor air·2008
Same author

Factors related to declining luteal function in women during the menopausal transition.

The Journal of clinical endocrinology and metabolism·2008
Same author

Premature menopause in a multi-ethnic population study of the menopause transition.

Human reproduction (Oxford, England)·2003
Same author

Assessing menstrual cycles with urinary hormone assays.

American journal of physiology. Endocrinology and metabolism·2002

Area of Science:

  • Epidemiology
  • Biostatistics

Background:

  • Case-control studies are crucial for investigating potential causes of diseases.
  • Understanding methodological nuances is vital for reliable results.

Purpose of the Study:

  • To outline the case-control study methodology.
  • To highlight potential pitfalls and biases.
  • To provide guidance on data analysis and causality assessment.

Main Methods:

  • Describes steps for selecting cases and controls.
  • Details methods for valid exposure and host information ascertainment.
  • Explains sample size determination and data analysis approaches.

Main Results:

  • Provides criteria for assessing causality in observed associations.

Related Experiment Videos

  • Compares strengths and limitations against the cohort approach.
  • Includes endocrinologic examples to illustrate methodologies.

    • Conclusions:

    • Case-control studies offer a valuable framework for etiological research.
    • Careful design and analysis are essential to minimize bias and ensure valid conclusions.