Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Giant cell arteritis with normal sedimentation rate

T Kansu, J J Corbett, P Savino

    Archives of Neurology
    |October 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Does the Order of Surgical Method of Training Affect Learning and Skill? A Comparison of Laparoscopy and Robotics.

    Journal of minimally invasive gynecology·2016
    Same author

    Atypical idiopathic intracranial hypertension: normal BMI and older patients.

    Neurology·2010
    Same author

    Mitigating the health impacts of pollution from oceangoing shipping: an assessment of low-sulfur fuel mandates.

    Environmental science & technology·2009
    Same author

    Idiopathic intracranial hypertension in men.

    Neurology·2008
    Same author

    Long-term follow-up of idiopathic intracranial hypertension: the Iowa experience.

    Neurology·2008
    Same author

    Skewed X inactivation in an X linked nystagmus family resulted from a novel, p.R229G, missense mutation in the FRMD7 gene.

    The British journal of ophthalmology·2007

    Giant cell arteritis can occur in elderly patients even with a normal erythrocyte sedimentation rate (ESR). Early clinical diagnosis and treatment are crucial to prevent severe complications of this condition.

    Area of Science:

    • Rheumatology
    • Internal Medicine
    • Vascular Biology

    Background:

    • Giant cell arteritis (GCA) is a systemic vasculitis primarily affecting large and medium arteries.
    • Elevated erythrocyte sedimentation rate (ESR) is a common inflammatory marker in GCA diagnosis.
    • Delayed diagnosis of GCA can lead to irreversible ischemic complications.

    Observation:

    • Two elderly patients presented with biopsy-proven giant cell arteritis.
    • Both patients exhibited normal erythrocyte sedimentation rate (ESR) levels.
    • Clinical symptoms were the primary indicators for suspicion of GCA.

    Findings:

    • Normal ESR does not exclude the diagnosis of giant cell arteritis.
    • Biopsy confirmation remains essential in cases with clinical suspicion despite normal inflammatory markers.

    Related Experiment Videos

  • This highlights the heterogeneity of GCA presentation.

    • Implications:

    • Clinicians should consider GCA in elderly patients with suggestive symptoms, irrespective of ESR.
    • Early initiation of corticosteroid therapy based on clinical suspicion is vital.
    • Relying solely on ESR may lead to missed or delayed diagnosis of GCA, increasing patient risk.