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Updated: Aug 24, 2026

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
Published on: January 29, 2020
Is beta-carotene an antioxidant?
1Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA. crabtree@vision.eri.harvard.edu
Abstract:
An hypothesis is presented that is opposed to the conventional viewpoint that beta-carotene is an in vivo free-radical scavenger. It is suggested that there are biochemical reasons why beta-carotene, other carotenoids, and especially their metabolites may be harmful to mammalian systems. Finally, the hypothesis that the macular pigment carotenoids, lutein and zeaxanthin, are free-radical scavengers is challenged.
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