Related Experiment Video
Updated: Aug 15, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Severe visual loss after autologous blood injection for mitomycin-C-associated hypotonous maculopathy
D W Lu1, A Azuara-Blanco, L J Katz
1William and Anna Goldberg Glaucoma Service and Research Laboratories, Wills Eye Hospital, Jefferson Medical College, Philadelphia, PA 19107, USA.
Abstract:
It has been shown that mitomycin-C increases the success rate of trabeculectomy; however, a rise in the incidence of postoperative complications has also been reported. Consequently, the use of antimetabolite is usually reserved for patients who are at high risk of surgical failure or for patients with advanced glaucoma in whom low intraocular pressure is desired. This report describes a patient who suffered severe visual loss which was a direct result of hypotonous maculopathy after trabeculectomy with mitomycin-C and various other complications from the subsequent interventions.

