Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Magnesium-containing carbonate apatites

I Mayer1, R Schlam, J D Featherstone

  • 1Department of Inorganic and Analytical Chemistry, Hebrew University, Jerusalem, Israel.

Journal of Inorganic Biochemistry
|April 1, 1997
PubMed
Summary

Magnesium incorporation into hydroxyapatite was investigated. This study shows magnesium stabilizes hydroxyapatite and influences its thermal decomposition and structure, impacting biomaterial applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TBCRC 035: randomized phase II pharmacodynamic study of standard and reduced-dose palbociclib with endocrine therapy in hormone receptor (HR)-positive previously treated metastatic breast cancer.

ESMO open·2026
Same author

Non-invasive sampling of water-borne hormones demonstrates individual consistency of the cortisol response to stress in laboratory zebrafish (Danio rerio).

Scientific reports·2022
Same author

Time course and management of key adverse events during the randomized phase III SOLAR-1 study of PI3K inhibitor alpelisib plus fulvestrant in patients with HR-positive advanced breast cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same author

Contrasting associations between breeding coloration and parasitism of male Arctic charr relate to parasite species and life cycle stage.

Scientific reports·2019
Same author

Introduction to ICNARA 3.

Advances in dental research·2018
Same author

Novel Anticaries and Remineralization Agents: Future Research Needs.

Journal of dental research·2018

Area of Science:

  • Materials Science
  • Biomaterials Engineering
  • Inorganic Chemistry

Background:

  • Hydroxyapatite (Ca10(PO4)6(OH)2) is a key biomaterial.
  • Understanding modifications to hydroxyapatite is crucial for developing advanced biomaterials.
  • Magnesium's role in apatite formation and stability requires further elucidation.

Purpose of the Study:

  • To investigate the incorporation of magnesium (Mg) into hydroxyapatite structures.
  • To analyze the effects of Mg on carbonate apatite formation and thermal stability.
  • To characterize the structural and morphological changes induced by Mg.

Main Methods:

  • Precipitation of hydroxyapatites at varying pH (7.0 and 9.0) with and without carbonate, and with different Mg concentrations.
  • Analysis using X-ray diffraction (XRD) for lattice constants, Infrared (IR) spectroscopy for carbonate substitution, and Scanning Electron Microscopy (SEM) for morphology.
  • Thermal decomposition studies up to 1000°C.

Main Results:

  • Magnesium incorporation into the apatite lattice was confirmed by Mg uptake, Ca/P ratios, and lattice constant data.
  • IR spectra indicated the formation of B-type carbonate apatites, with carbonate substituting for phosphate groups.
  • Thermal decomposition of carbonate apatites was more gradual at pH 9.0 compared to pH 7.0.
  • Apatites synthesized without added carbonate transformed to beta-tricalcium phosphate (TCP) at ~700°C, with increased Mg incorporation enhancing TCP stabilization.
  • SEM micrographs revealed increased crystallite size with Mg precipitation, supporting Mg incorporation.

Conclusions:

  • Magnesium is effectively incorporated into hydroxyapatite and carbonate apatite structures.
  • Magnesium influences the thermal stability of hydroxyapatite, particularly in the presence of carbonate.
  • Magnesium incorporation stabilizes beta-tricalcium phosphate (TCP), suggesting potential applications in bone regeneration materials.

Related Experiment Videos