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Related Experiment Videos

What factors influence whether placentas are submitted for pathologic examination?

V J Booth1, K B Nelson, J M Dambrosia

  • 1Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-9130, USA.

American Journal of Obstetrics and Gynecology
|March 1, 1997
PubMed
Summary

Placental examination submission is primarily driven by surgical delivery, not maternal or infant conditions. Cesarean sections, both elective and indicated, significantly increase the likelihood of placental pathology review.

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Area of Science:

  • Obstetrics and Gynecology
  • Pathology
  • Pediatrics

Background:

  • Placental examination is crucial for understanding perinatal complications.
  • Factors influencing placental submission for pathologic examination are not well-defined.

Purpose of the Study:

  • To identify factors associated with the submission of placentas for pathologic examination in a population-based study.

Main Methods:

  • A population-based study analyzed data from 627 singleton survivors to age 3 years.
  • Cases had moderate-to-severe cerebral palsy; controls were randomly selected infants.

Main Results:

  • Placentas were submitted for 24% of children studied.
  • Submission rates were higher for low birth weight (<1500 gm) and cesarean section deliveries (p < 0.0001).

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  • Maternal/neonatal disorders, despite indications for examination, did not correlate with submission.

    • Conclusions:

    • Surgical delivery (cesarean section) is the primary determinant for placental submission, irrespective of indication.
    • Maternal and infant conditions had minimal impact on placental submission likelihood.