Mutation, ageing, and ovarian cancer

DNA repair modulates the vulnerability of the developing brain to alkylating agents.

DNA repair·2009

Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death.

DNA repair·2004

Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress.

Oncogene·2001

Common polymorphisms and somatic mutations in human base excision repair genes in ovarian and endometrial cancers.

Mutation research·2001

Somatic cell mutations: can they provide a link between aging and cancer?

Mechanisms of ageing and development·2000

Biallelic methylation and silencing of mouse Aprt in normal kidney cells.

Cancer research·2000

[177Lu]Lu-PSMA-617 in patients with PSMA-positive metastatic androgen pathway modulator-naive/sensitive prostate cancer (PSMAddition): a phase 3 randomised, controlled trial.

Lancet (London, England)·2026

Multivessel coronary artery bypass grafting via small thoracotomy versus sternotomy (MIST): an investigator-initiated, international, open-label, randomised controlled trial.

Lancet (London, England)·2026

Efficacy and safety of once-weekly subcutaneous zenagamtide, a novel unimolecular GLP-1 and amylin receptor agonist, in type 2 diabetes: a multicentre, randomised, parallel, double-blind, placebo-controlled, dose-finding, phase 2 trial.

Lancet (London, England)·2026

Efficacy and safety of once-daily oral zenagamtide, a novel unimolecular GLP-1 and amylin receptor agonist, in adults with type 2 diabetes: a multicentre, randomised, parallel, double-blind, placebo-controlled, dose-finding, phase 2 trial.

Lancet (London, England)·2026

Case Report: Papillon-Lefèvre syndrome beyond keratoderma: two index presentations and sibling screening in two families.

Frontiers in immunology·2026

Gene Therapy for Dystrophic Epidermolysis Bullosa.

Experimental dermatology·2026

Charting intratumor heterogeneity from bench to bedside.

Nature cancer·2026

Somatic mutations and genome mosaicism in aging and disease.

Experimental & molecular medicine·2026

A functional landscape for chromosome 17q in neuroblastoma: balancing replication stress and genomic stability.

British journal of cancer·2026

Role of pks + Escherichia coli in colorectal cancer: Mechanisms, clinical evidence, and therapeutic perspective.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases·2026

Related Experiment Videos

Mutation, ageing, and ovarian cancer

Related Concept Videos

DNA repair modulates the vulnerability of the developing brain to alkylating agents.

Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death.

Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress.

Common polymorphisms and somatic mutations in human base excision repair genes in ovarian and endometrial cancers.

Somatic cell mutations: can they provide a link between aging and cancer?

Biallelic methylation and silencing of mouse Aprt in normal kidney cells.

[177Lu]Lu-PSMA-617 in patients with PSMA-positive metastatic androgen pathway modulator-naive/sensitive prostate cancer (PSMAddition): a phase 3 randomised, controlled trial.

Multivessel coronary artery bypass grafting via small thoracotomy versus sternotomy (MIST): an investigator-initiated, international, open-label, randomised controlled trial.

Efficacy and safety of once-weekly subcutaneous zenagamtide, a novel unimolecular GLP-1 and amylin receptor agonist, in type 2 diabetes: a multicentre, randomised, parallel, double-blind, placebo-controlled, dose-finding, phase 2 trial.

Efficacy and safety of once-daily oral zenagamtide, a novel unimolecular GLP-1 and amylin receptor agonist, in adults with type 2 diabetes: a multicentre, randomised, parallel, double-blind, placebo-controlled, dose-finding, phase 2 trial.

Case Report: Papillon-Lefèvre syndrome beyond keratoderma: two index presentations and sibling screening in two families.

Gene Therapy for Dystrophic Epidermolysis Bullosa.

Charting intratumor heterogeneity from bench to bedside.

Somatic mutations and genome mosaicism in aging and disease.

A functional landscape for chromosome 17q in neuroblastoma: balancing replication stress and genomic stability.

Role of pks + Escherichia coli in colorectal cancer: Mechanisms, clinical evidence, and therapeutic perspective.

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Mutation, ageing, and ovarian cancer

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