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Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Chromosome analyses in a rhabdoid tumor of the brain
K Klopfenstein1, S Soukup, R Blough
1Department of Hematology/Oncology, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
Cancer Genetics and Cytogenetics
|February 1, 1997
Abstract:
A malignant rhabdoid tumor of the brain from a 19-month-old child was studied. Two related clones, 46,XX,-8,+der(8)t(8;22)(p11;q?12)x2,-22,del(22)(q12q?13) and 46,XX-8,+der(8)t(8;22) (p11;q?12) x2,-22,r(22) were found after chromosome analyses of primary and recurrent tumor, and multiple nude mouse passages of the tumor. Breakpoints were studied using FISH.

