Base deficit: an indicator of tissue hypoperfusion

The clinical parameters used to evaluate hypovolemia each lack a certain degree of sensitivity and specificity. Indicators that reflect metabolic processes may have more potential for recognizing subtle changes. The use of base deficit for monitoring tissue hypoperfusion is discussed, along with a review of the research. Nurses caring for trauma patients may find monitoring base deficit to be a valuable aid in determining whether the patient continues to have hypoperfusion.